International Review of Neurobiology Volume 48 1st Edition by Ronald Bradley, Adron Harris, Peter Jenner 0123668484 9780123668486 by Ronald J. Bradley, R. Adron Harris, Peter Jenner 978-0-12-366848-6 instant download after payment.

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Product details:

ISBN 10: 0123668484

ISBN 13: 9780123668486

Author: Ronald J. Bradley, R. Adron Harris, Peter Jenner

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

Table of contents:

Chapter 1. Assembly and Intracellular Trafficking of GABAA Receptors

I. Introduction

II. Assembly of GABAA Receptors

III. Surface Targeting and Intracellular Sorting of GABAA Receptors

IV. GABAA Receptor-Clustering Proteins

V. Endocytosis and Recycling of GABAA Receptors

References

Chapter 2. Subcellular Localization and Regulation of GABAA Receptors and Associated Proteins

I. Introduction

II. Functional Significance of GABAergic Inhibition in the Brain

III. Structural Anatomy of GABAergic Synapses

IV. Structure of GABAA Receptors

V. Subcellular Localization of GABAA Receptor Subtypes

VI. Factors Implicated in Exocytosis and Endocytosis of GABAA Receptors

VII. Synaptic Anchoring of GABAC Receptors

VIII. GABAA Receptor-Associated Signaling Proteins

IX. Synaptic Plasticity

X. Concluding Remarks

References

Chapter 3. D1 Dopamine Receptors

I. Introduction

II. Localization and Function of D1-like Receptors

III. Development of Drugs for D1-like Receptors

IV. Therapeutic and Functional Actions of D1 Receptor Agonists and Antagonists

V. Conclusions and Future Goals

References

Chapter 4. Molecular Modeling of Ligand-Gated Ion Channels: Progress and Challenges

I. The Challenge of Modeling Transmembrane Ion Channels

II. Overview of Molecular Modeling Principles

III. Experimental Data: Techniques and Results

IV. Molecular Models

V. Summary

References

Chapter 5. Alzheimer’s Disease: Its Diagnosis and Pathogenesis

I. Introduction

II. Diagnostic Issues

III. Pathogenesis

IV. Genetic Influences

V. Inflammation and Anti-inflammatory Drugs

VI. Estrogen Therapy

VII. Vascular Pathology in AD

References

Chapter 6. DNA Arrays and Functional Genomics in Neurobiology

I. Introduction

II. DNA Array Formats and Technique

III. Applications in Neurobiology

IV. Caveats and Future Needs

V. Conclusion

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