Parameters For Pesticide Qsar And Pbpkpd Models For Human Risk Assessment James B Knaak by James B. Knaak, Charles Timchalk, And Rogelio Tornero-velez (eds.) 9780841226456, 9780841226463, 0841226458, 0841226466 instant download after payment.

Content: Parameters for pesticide QSAR and PBPK/PD models to inform human risk assessments --
Chiral chemistry and toxicity assessments for pyrethroid pesticides --
Direct chiral separation of pyrethroid isomers by HPLC with chiral stationary phases --
Biotransformation and enzymes responsible for metabolism of pyrethroids in mammals --
Characterization of potential age-related differences in pyrethroid pharmacokinetics --
15 factors of percutaneous penetration of pesticides --
Percutaneous absorption of pesticide formulations --
Human metabolic interactions of pesticides : inhibition, induction and activation --
Paraoxonase 1 (PON1) status in risk assessment for organophosphate exposure and pharmacokinetics --
Carboxylesterases : a multifunctional enzyme involved in pesticide and lipid metabolism --
Behavioral changes in adult and young rats as indications of cholinesterase inhibition --
Comparison of esterase sensitivity, metabolic efficiency, and toxicity levels of two organophosphorus insecticides, parathion and chlorpyrifos --
Regional brain dosimetry for the organophosphorus insecticide chlorpyrifos in the preweanling rat --
Pyrethroid actions on sodium channels : isoform and species specificity --
In vitro and in vivo experimental data for development and use of pharmacokinetic models for in vitro to in vivo extrapolation of pyrethroid insecticides --
In silico strategies for modeling stereoselective metabolism of pyrethroids --
Quantitative structure-activity relationships for organophosphate enzyme inhibition --
Computational approaches for developing informative prior distributions for bayesian calibration of PBPK models --
Use of cytochrome P450-specific parameters and human biomarker data to develop a human physiologically based pharmacokinetic/pharmacodynamic model for dermal chlorpyrifos exposure --
Use of in vitro data in PBPK models : an example of in vitro to in vivo extrapolation with carbaryl.