Vascular Complications in Human Disease Mechanisms and Consequences 1st Edition by David Abraham, Clive Handler, Michael Dashwood, Gerry Coghlan 184628919X 9781846289194 by David Abraham, Clive Handler, Michael Dashwood, Gerry Coghlan 1846289181 instant download after payment.

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Product details:

ISBN 10: 184628919X 

ISBN 13: 9781846289194

Author: David Abraham, Clive Handler, Michael Dashwood, Gerry Coghlan

Arterial disease and inflammation are fundamental causes of many medical conditions. Recently, there have been several major advances in our understanding of the causes of diseases affecting the heart, lungs, kidneys, skin and blood vessels. The role of endothelium derived growth factors, nitric oxide and other messengers in vascular disease has been more clearly defined. New treatments targeting these molecular disorders are being used with beneficial effects. Further progress depends on a combined approach embracing basic and clinical research so that treatments of common, important diseases can be designed intelligently and logically. "Vascular Complications in Human Disease" presents our understanding of vascular disease, in reviews of the main strands of basic and clinical research written by leading international experts. It also identifies routes for further fruitful research and development. This concise and carefully edited book, avoiding repetition, includes the full spectrum of basic research which is not covered in other textbooks.

Table of contents:

1. Therapy for Pulmonary Vascular Disease: Past, Present, and Future

2. Nitric Oxide Axis in Cardiopulmonary Disease

3. Endothelin Signaling in the Cardiomyocyte

4. TGF-β/BMP Signaling in Pulmonary Vascular Disease

5. Endothelin System in Chronic Kidney Disease

6. Endothelial Activation in Inflammation: Lessons Learned from E-Selectin

7. Pathogenic Mediators of Vessel Sclerosis: Regulation of Vascular Smooth Muscle Cell Proliferation by Growth Factors, the Extracellular Matrix, and the Endothelium

8. Control of Interstitial Fluid Homeostasis: Roles of Growth Factors and Integrins

9. Vascular Complications of Systemic Sclerosis: A Molecular Perspective

10. Therapeutic Options for Preventing Transplant-Related Progressive Renal and Vascular Injury

11. Current State of Medical Therapies for Peripheral Vascular Disease

12. Advantages of Harvesting the Saphenous Vein for Coronary Artery Bypass Surgery Using the “No-Touch” Technique

13. Toward the Prevention of Vein Graft Failure

14. Statins and Cholesterol: How Low Can You Go?

15. Endothelin-1-Promoting Actions in the Growth and Angiogenesis of Solid Cancers

16. Gene Therapy for Apolipoprotein A-I and HDL—The Ultimate Treatment for Atherosclerosis

17. ETS Family of Transcription Factors and the Vascular System

18. Aortic Valve: From Function to Tissue Engineering

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Tags: David Abraham, Clive Handler, Michael Dashwood, Complications